IFNA16

Across TCGA pan-cancer cohorts, IFNA16 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of IFNA16’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where IFNA16 RNA is repressed in tumor relative to normal tissue. In most cancer types IFNA16 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC and KICH are the cancer types where IFNA16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IFNA16 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.062	<.001	9	view →
KICH	All	All	−0.085	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

IFNA16–KIRC

Open the KIRC breakdown →