IFNA16

Across TCGA cell cohorts, IFNA16 RNA expression is significantly associated with the mutation status of many other genes, with 31 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible IFNA16-associated genes across cancer lineages are SPATA17, POLRMT, and ATP8B4. Each is linked with IFNA16 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA16-to-partner and partner-to-IFNA16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA17 grouped by IFNA16-low versus IFNA16-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA16→partner) and Y-score (partner→IFNA16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	SPATA17 →	+4.584	+0.042	.001	<.001	3	1
BLOOD_Lymphoma	POLRMT →	+4.247	+0.010	.004	<.001	3	1
BLOOD_Lymphoma	ATP8B4 →	+4.247	+0.010	.004	<.001	3	1
BLOOD_Lymphoma	ADGRB2 →	+4.247	+0.010	.004	<.001	3	1
BLOOD_Lymphoma	ADCY10 →	+3.925	+0.008	.006	<.001	3	1
BLOOD_Lymphoma	HEATR6 →	+4.247	+0.010	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

SPATA17 by IFNA16 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →