Across TCGA patient cohorts, IFIT1B mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFIT1B-associated genes across cancer lineages are EGFR, eIF4G, and ERK2. Each is linked with IFIT1B in more than 1 cancer types. Because this analysis shows association rather than direction, both IFIT1B-to-partner and partner-to-IFIT1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT1B→partner) and Y-score (partner→IFIT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.269	-3.584	<.001	.002	3	1
UCEC	eIF4G →	+0.387	+3.321	.004	.010	3	1
UCEC	ERK2 →	+0.291	+3.321	<.001	.009	3	1
UCEC	JNK_pT183_Y185 →	-0.208	-2.584	.004	.010	3	1
UCEC	Ku80 →	+0.220	+2.820	.033	.001	3	1
UCEC	MEK1 →	+0.606	+3.584	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

IFIT1B survival (RNA) · tumor vs normal (RNA) · all IFIT1B data types