Across TCGA cell cohorts, IFIT1B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IFIT1B-associated genes across cancer lineages are MAGEB4, C16orf96, and CCDC195. Each is linked with IFIT1B in more than 1 cancer types. Because this analysis shows association rather than direction, both IFIT1B-to-partner and partner-to-IFIT1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT1B→partner) and Y-score (partner→IFIT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.014	+4.000	<.001	<.001	3	1
LARGE_INTESTINE	C16orf96 →	+0.519	+3.520	.003	.005	3	1
LARGE_INTESTINE	CCDC195 →	+0.045	+3.297	<.001	.002	3	1
LARGE_INTESTINE	IL20 →	+0.239	+2.984	<.001	.005	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

IFIT1B survival (RNA) · tumor vs normal (RNA) · all IFIT1B data types