IER3IP1

Across TCGA patient cohorts, IER3IP1 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IER3IP1-associated genes across cancer lineages are RNU4-65P, RNU6-281P, and MIR6803. Each is linked with IER3IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IER3IP1-to-partner and partner-to-IER3IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-65P grouped by IER3IP1-low versus IER3IP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IER3IP1→partner) and Y-score (partner→IER3IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-65P →	+0.508	+5.453	<.001	.002	3	2
SKCM	RNU6-281P →	+0.373	+7.816	<.001	.008	3	1
UCEC	MIR6803 →	+0.556	+7.478	<.001	<.001	3	1
UCEC	RNU7-10P →	+0.949	+4.423	.002	.006	3	1
UCEC	MIR8053 →	+0.819	+5.582	<.001	.002	3	1
UCEC	MIR3168 →	+1.177	+4.633	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

RNU4-65P by IER3IP1 expression — UCEC

Explore this box plot interactively →