IER2

Across TCGA patient cohorts, IER2 mutation is significantly associated with the RNA expression of many other genes, with 676 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IER2-associated genes across cancer lineages are RNA5SP93, RNU6-633P, and SNORD116-19. Each is linked with IER2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IER2-to-partner and partner-to-IER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP93 grouped by IER2-low versus IER2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IER2→partner) and Y-score (partner→IER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP93 →	+0.666	+5.087	<.001	.002	3	2
COAD	RNU6-633P →	+0.896	+3.374	<.001	.008	3	2
COAD	SNORD116-19 →	+0.951	+3.622	<.001	.002	3	2
COAD	RNU7-169P →	+0.527	+4.225	.009	.007	3	2
COAD	RN7SL617P →	+0.531	+3.602	<.001	.005	3	2
COAD	RN7SL714P →	+0.321	+4.821	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 676 associations by consensus.

RNA5SP93 by IER2 expression — COAD

Explore this box plot interactively →