IDH3B

Across TCGA patient cohorts, IDH3B protein abundance is significantly associated with the RNA expression of many other genes, with 15,449 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IDH3B-associated genes across cancer lineages are IDH3A, SERPINH1, and COX5A. Each is linked with IDH3B in more than 5 cancer types. Because this analysis shows association rather than direction, both IDH3B-to-partner and partner-to-IDH3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDH3B versus IDH3A in OV, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDH3B→partner) and Y-score (partner→IDH3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IDH3A →	+0.961	+0.524	<.001	<.001	3	6
BRCA	SERPINH1 →	-0.645	-0.266	.005	<.001	3	5
OV	COX5A →	+0.571	+0.324	<.001	<.001	3	5
PDAC	ATP10B →	+1.260	+0.294	.001	<.001	3	4
OV	RAB38 →	-1.005	-0.375	.004	.001	3	4
COAD	SLC43A3 →	-0.749	-0.230	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,449 associations by consensus.

IDH3B vs IDH3A — OV

Explore this scatter interactively →