IDH1-AS1

Across TCGA patient cohorts, IDH1-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,137 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible IDH1-AS1-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, Peroxisome fission, and Protein maturation by iron-sulfur cluster transfer. Each is linked with IDH1-AS1 in more than 22 cancer types. Because this analysis shows association rather than direction, both IDH1-AS1-to-partner and partner-to-IDH1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by IDH1-AS1-low versus IDH1-AS1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IDH1-AS1→partner) and Y-score (partner→IDH1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[4Fe-4S] cluster assembly →	+0.060	+0.771	<.001	<.001	3	23
PAAD	Peroxisome fission →	+0.053	+0.398	<.001	<.001	3	23
ESCA	Protein maturation by iron-sulfur cluster transfer →	+0.060	+0.429	.003	<.001	2	23
ESCA	tRNA threonylcarbamoyladenosine modification →	+0.041	+0.395	<.001	<.001	3	21
THYM	Obsolete cyclic-nucleotide-mediated signaling →	-0.024	-0.418	<.001	<.001	3	20
ESCA	Cyclic nucleotide metabolic process →	-0.045	-0.413	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,137 associations by consensus.

[4Fe-4S] cluster assembly by IDH1-AS1 expression — DLBC

Explore this box plot interactively →