Across TCGA patient cohorts, HTT-AS RNA expression is significantly associated with the go_rna of many other GO terms, with 6,754 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HTT-AS-associated GO terms across cancer lineages are Obsolete histone methylation, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with HTT-AS in more than 22 cancer types. Because this analysis shows association rather than direction, both HTT-AS-to-partner and partner-to-HTT-AS results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTT-AS→partner) and Y-score (partner→HTT-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Obsolete histone methylation →	+0.054	+0.090	<.001	<.001	3	23
UVM	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.071	+0.115	<.001	<.001	3	23
UVM	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.070	+0.133	<.001	<.001	3	23
ESCA	Circadian regulation of gene expression →	+0.060	+0.180	<.001	<.001	3	22
STAD	Organelle fusion →	+0.046	+0.104	<.001	<.001	3	22
STAD	Nucleotide-excision repair →	+0.046	+0.081	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,754 associations by consensus.

Exploration

HTT-AS survival (RNA) · tumor vs normal (RNA) · all HTT-AS data types