HTR5BP

Across TCGA patient cohorts, HTR5BP protein abundance is significantly associated with the RNA expression of many other genes, with 794 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HTR5BP-associated genes across cancer lineages are SGCG, PCDHB2, and PRTN3. Each is linked with HTR5BP in more than 1 cancer types. Because this analysis shows association rather than direction, both HTR5BP-to-partner and partner-to-HTR5BP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR5BP versus SGCG in UCEC, with a Pearson correlation of -0.94.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR5BP→partner) and Y-score (partner→HTR5BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SGCG →	-1.595	-0.750	.009	<.001	3	2
UCEC	PCDHB2 →	-2.690	-0.815	.002	.003	3	1
UCEC	PRTN3 →	-0.385	-0.788	.001	<.001	3	1
UCEC	HRNR →	-3.305	-0.800	.003	.006	3	1
UCEC	FLG-AS1 →	-2.150	-0.815	<.001	.003	3	1
UCEC	PDCD5P2 →	-1.065	-0.788	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 794 associations by consensus.

HTR5BP vs SGCG — UCEC

Explore this scatter interactively →