HTR5A

Across TCGA patient cohorts, HTR5A RNA expression is significantly associated with the protein abundance of many other proteins, with 9,950 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HTR5A-associated proteins across cancer lineages are CLASRP_S456, REPS1, and AP3B1. Each is linked with HTR5A in more than 1 cancer types. Because this analysis shows association rather than direction, both HTR5A-to-partner and partner-to-HTR5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR5A versus CLASRP_S456 in GBM, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR5A→partner) and Y-score (partner→HTR5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CLASRP_S456 →	-0.575	-0.392	.001	.005	3	2
BRCA	REPS1 →	+0.270	+0.008	.001	.004	3	2
GBM	AP3B1 →	-0.273	-0.384	<.001	<.001	3	2
BRCA	MDH1_S333 →	+0.560	+0.009	.007	.008	3	2
GBM	SYNGAP1_S165 →	+1.369	+0.453	<.001	<.001	3	2
GBM	NF1_S2515 →	+0.510	+0.360	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,950 associations by consensus.

HTR5A vs CLASRP_S456 — GBM

Explore this scatter interactively →