HTR5A

Across TCGA patient cohorts, HTR5A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,931 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HTR5A-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Negative regulation of cilium assembly, and Microtubule depolymerization. Each is linked with HTR5A in more than 9 cancer types. Because this analysis shows association rather than direction, both HTR5A-to-partner and partner-to-HTR5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribose phosphate biosynthetic process grouped by HTR5A-low versus HTR5A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR5A→partner) and Y-score (partner→HTR5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribose phosphate biosynthetic process →	+0.070	+0.042	<.001	<.001	3	9
SCLC	Negative regulation of cilium assembly →	+0.091	+0.343	.001	.002	3	9
THYM	Microtubule depolymerization →	+0.044	+0.953	<.001	<.001	3	9
STAD	Regulation of Ras protein signal transduction →	+0.057	+0.044	<.001	<.001	3	9
STAD	Microtubule polymerization →	+0.065	+0.047	<.001	<.001	3	9
SCLC	Negative regulation of cytoskeleton organization →	+0.060	+0.233	<.001	.004	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,931 associations by consensus.

Ribose phosphate biosynthetic process by HTR5A expression — STAD

Explore this box plot interactively →