Across TCGA cell cohorts, HTR3D RNA expression is significantly associated with the RNA expression of many other genes, with 1,028 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible HTR3D-associated genes across cancer lineages are OR5C1, KRTAP4-4, and NCR2. Each is linked with HTR3D in more than 3 cancer types. Because this analysis shows association rather than direction, both HTR3D-to-partner and partner-to-HTR3D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR3D→partner) and Y-score (partner→HTR3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR5C1 →	+0.137	+0.007	<.001	.007	3	4
LARGE_INTESTINE	KRTAP4-4 →	+0.207	+0.008	<.001	.007	3	4
LUNG_NSCLC_LUSC	NCR2 →	+0.029	+0.017	.004	.004	3	3
UPPER_AERODIGESTIVE_TRACT	FAM47B →	+0.049	+0.036	.001	.001	3	3
UPPER_AERODIGESTIVE_TRACT	FSCB →	+0.065	+0.048	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	KRTAP10-9 →	+0.106	+0.036	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,028 associations by consensus.

Exploration

HTR3D survival (RNA) · tumor vs normal (RNA) · all HTR3D data types