HTR3B

Across TCGA patient cohorts, HTR3B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,203 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HTR3B-associated proteins across cancer lineages are TMF1_T401, NDEL1_S231, and NCOR1_S1263. Each is linked with HTR3B in more than 3 cancer types. Because this analysis shows association rather than direction, both HTR3B-to-partner and partner-to-HTR3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR3B versus TMF1_T401 in BRCA, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR3B→partner) and Y-score (partner→HTR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMF1_T401 →	-0.485	-0.025	<.001	.002	3	4
GBM	NDEL1_S231 →	+0.979	+0.350	<.001	<.001	3	3
PDAC	NCOR1_S1263 →	-0.656	-0.027	<.001	.003	3	2
GBM	PAIP2 →	-0.192	-0.200	.001	<.001	3	2
GBM	TTC9 →	+0.344	+0.227	.002	<.001	3	2
GBM	RPN2 →	-0.320	-0.338	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,203 associations by consensus.

HTR3B vs TMF1_T401 — BRCA

Explore this scatter interactively →