HTR1E

Across TCGA patient cohorts, HTR1E protein abundance is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HTR1E-associated genes across cancer lineages are SERPINB12, NUDT4B, and ZFYVE9P2. Each is linked with HTR1E in more than 1 cancer types. Because this analysis shows association rather than direction, both HTR1E-to-partner and partner-to-HTR1E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR1E versus SERPINB12 in GBM, with a Pearson correlation of -0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR1E→partner) and Y-score (partner→HTR1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINB12 →	-0.096	-0.613	<.001	.008	2	1
GBM	NUDT4B →	-0.100	-0.613	<.001	.008	2	1
GBM	ZFYVE9P2 →	-0.530	-0.613	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

HTR1E vs SERPINB12 — GBM

Explore this scatter interactively →