heat shock protein family E (Hsp10) member 1 pseudogene 5Genealiases: []
Q-omics provides the consensus-scored HSPE1P5 profile across patient tissues and cancer cell-line models. HSPE1P5 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, HSPE1P5 is differentially expressed in 11, with the highest sampling consensus in COAD. Additionally, HSPE1P5 RNA expression shows 11,246 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UCEC, COAD, and THYM as cancer lineages where HSPE1P5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HSPE1P5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HSPE1P5 survival associations across molecular data types. HSPE1P5 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HSPE1P5 RNA expression–survival associations across cancer types. High HSPE1P5 expression shows unfavorable associations in UCEC, ACC, LIHC, LUAD and SKCM, but favorable associations in UVM. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .009). Together, the overview and detailed table identify UCEC as the clearest survival context for HSPE1P5 RNA expression.
This table summarizes HSPE1P5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for HSPE1P5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HSPE1P5 shows lower tumor expression in BRCA and higher tumor expression in COAD, THCA, LUAD, BLCA and PAAD. The COAD box plot shows higher HSPE1P5 RNA expression in tumor versus normal tissue (log2 FC = +0.661, t-test p < 0.001).
This table shows molecular features associated with HSPE1P5 in patient tissues and cancer cell lines. In patient samples, HSPE1P5 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
