HSPE1P5

Across TCGA pan-cancer cohorts, HSPE1P5 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated HSPE1P5 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher HSPE1P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HSPE1P5 expression acts as an unfavorable survival marker, although some lineages such as UVM and TGCT show a favorable association.

UCEC, ACC, and LIHC are the cancer types where HSPE1P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.615	0.763	.009	60	view →
ACC	DFS	Median	II,III,IV	0.382	0.686	.001	54	view →
LIHC	DFS	Median	All	0.191	0.399	<.001	52	view →
LUAD	DFS	Tertile	All	0.709	0.843	<.001	39	view →
UVM	OS	Tertile	II,III,IV	1.000	0.738	.013	30	view →
SKCM	OS	Median	IV	0.391	0.773	.007	24	view →
CHOL	OS	Tertile	II,III,IV	0.080	0.740	.026	18	view →
KIRC	DFS	Quartile	III,IV	0.624	0.792	.011	16	view →
BRCA	OS	Tertile	IV	0.379	0.813	.003	16	view →
ESCA	OS	Median	II,III,IV	0.387	0.574	.006	16	view →
STAD	OS	Tertile	II,III,IV	0.592	0.797	.027	15	view →
TGCT	DFS	Quartile	All	0.969	0.594	<.001	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

HSPE1P5–UCEC (OS)

Open the UCEC breakdown →