heat shock protein family E (Hsp10) member 1 pseudogene 4Genealiases: []
Q-omics provides the consensus-scored HSPE1P4 profile across patient tissues and cancer cell-line models. HSPE1P4 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in LUSC. Among the 18 cancer types available for tumor–normal comparison, HSPE1P4 is differentially expressed in 11, with the highest sampling consensus in HNSC. Additionally, HSPE1P4 RNA expression shows 10,871 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight LUSC, HNSC, and ACC as cancer lineages where HSPE1P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HSPE1P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HSPE1P4 survival associations across molecular data types. HSPE1P4 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HSPE1P4 RNA expression–survival associations across cancer types. High HSPE1P4 expression shows unfavorable associations in UVM, ACC, LIHC, HNSC and ESCA, but favorable associations in LUSC. The LUSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify LUSC as the clearest survival context for HSPE1P4 RNA expression.
This table summarizes HSPE1P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for HSPE1P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HSPE1P4 shows higher tumor expression in HNSC, BLCA, BRCA, STAD, COAD and LIHC. The HNSC box plot shows higher HSPE1P4 RNA expression in tumor versus normal tissue (log2 FC = +0.193, t-test p < 0.001).
This table shows molecular features associated with HSPE1P4 in patient tissues and cancer cell lines. In patient samples, HSPE1P4 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
