Across TCGA pan-cancer cohorts, HSPE1P11 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of HSPE1P11’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where HSPE1P11 RNA is repressed in tumor relative to normal tissue. In most cancer types HSPE1P11 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and LUAD are the cancer types where HSPE1P11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPE1P11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.262	<.001	7	view →
KICH	All	All	−0.199	<.001	4	view →
LUAD	All	IV	−0.715	<.001	2	view →
LUSC	All	All	−0.188	.004	2	view →
CHOL	All	All	+0.310	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: HSPE1P11 RNA expression & survival · all HSPE1P11 data types