heat shock protein family E (Hsp10) member 1 pseudogene 11Genealiases: []
Q-omics provides the consensus-scored HSPE1P11 profile across patient tissues and cancer cell-line models. HSPE1P11 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, HSPE1P11 is differentially expressed in 5, with the highest sampling consensus in THCA. Additionally, HSPE1P11 RNA expression shows 11,944 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UVM, and THCA as cancer lineages where HSPE1P11 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HSPE1P11 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HSPE1P11 survival associations across molecular data types. HSPE1P11 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HSPE1P11 RNA expression–survival associations across cancer types. High HSPE1P11 expression shows unfavorable associations in UVM, THCA, SKCM and COAD, but favorable associations in LUSC and LUAD. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify UVM as the clearest survival context for HSPE1P11 RNA expression.
This table summarizes HSPE1P11 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for HSPE1P11. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HSPE1P11 shows lower tumor expression in THCA, KICH, LUAD and LUSC and higher tumor expression in CHOL. The THCA box plot shows higher HSPE1P11 RNA expression in normal versus tumor tissue (log2 FC = −0.262, t-test p < 0.001).
This table shows molecular features associated with HSPE1P11 in patient tissues and cancer cell lines. In patient samples, HSPE1P11 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
