HSPE1

Across TCGA cell cohorts, HSPE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,762 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HSPE1-associated GO terms across cancer lineages are Mitochondrial gene expression, Protein insertion into mitochondrial inner membrane, and Endoplasmic reticulum unfolded protein response. Each is linked with HSPE1 in more than 16 cancer types. Because this analysis shows association rather than direction, both HSPE1-to-partner and partner-to-HSPE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by HSPE1-low versus HSPE1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPE1→partner) and Y-score (partner→HSPE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial gene expression →	+0.107	+1.200	<.001	<.001	3	17
BREAST	Protein insertion into mitochondrial inner membrane →	+0.092	+0.731	<.001	.001	3	16
STOMACH	Endoplasmic reticulum unfolded protein response →	-0.103	-1.270	<.001	.001	3	16
BONE	RNA 5'-end processing →	+0.113	+1.254	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication checkpoint signaling →	+0.171	+1.469	<.001	<.001	3	15
BONE	Response to endoplasmic reticulum stress →	-0.090	-1.229	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,762 associations by consensus.

Mitochondrial gene expression by HSPE1 expression — BONE

Explore this box plot interactively →