HSPE1-MOB4

Across TCGA patient cohorts, HSPE1-MOB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,728 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSPE1-MOB4-associated GO terms across cancer lineages are Positive regulation of chromosome condensation, CENP-A containing chromatin assembly, and Maturation of 5.8S rRNA. Each is linked with HSPE1-MOB4 in more than 20 cancer types. Because this analysis shows association rather than direction, both HSPE1-MOB4-to-partner and partner-to-HSPE1-MOB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome condensation grouped by HSPE1-MOB4-low versus HSPE1-MOB4-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPE1-MOB4→partner) and Y-score (partner→HSPE1-MOB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Positive regulation of chromosome condensation →	+0.120	+0.630	<.001	<.001	3	21
ACC	CENP-A containing chromatin assembly →	+0.082	+0.497	<.001	<.001	3	21
TGCT	Maturation of 5.8S rRNA →	+0.042	+0.153	<.001	<.001	3	20
ACC	Mitotic spindle elongation →	+0.067	+0.449	<.001	<.001	3	19
ACC	Chromosome condensation →	+0.077	+0.557	<.001	<.001	2	20
ACC	5S class rRNA transcription by RNA polymerase III →	+0.056	+0.634	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,728 associations by consensus.

Positive regulation of chromosome condensation by HSPE1-MOB4 expression — ACC

Explore this box plot interactively →