HSPE1-MOB4

Across TCGA pan-cancer cohorts, HSPE1-MOB4 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of HSPE1-MOB4’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where HSPE1-MOB4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HSPE1-MOB4 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LIHC, LUAD, and LUSC are the cancer types where HSPE1-MOB4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPE1-MOB4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.099	<.001	8	view →
LUAD	All	All	+0.166	<.001	7	view →
LUSC	All	All	+0.236	<.001	5	view →
STAD	All	All	+0.101	.002	5	view →
BRCA	All	II,III,IV	+0.151	<.001	4	view →
COAD	All	All	+0.142	.007	4	view →
BLCA	Male	IV	+0.250	.013	1	view →
KIRC	Female	IV	+0.165	.024	1	view →
CHOL	All	All	+0.153	.009	1	view →
ESCA	All	All	+0.120	.039	1	view →
HNSC	Female	II,III,IV	+0.110	.048	1	view →
THCA	All	All	−0.051	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

HSPE1-MOB4–LIHC

Open the LIHC breakdown →