HSPB8

Across TCGA patient cohorts, HSPB8 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,478 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSPB8-associated proteins across cancer lineages are HSPB8_T87, BAG3, and HSPB8_S57. Each is linked with HSPB8 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSPB8-to-partner and partner-to-HSPB8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB8 versus HSPB8_T87 in BRCA, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB8→partner) and Y-score (partner→HSPB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSPB8_T87 →	+1.069	+2.376	<.001	<.001	3	9
GBM	BAG3 →	+0.647	+1.634	<.001	<.001	3	9
HNSC	HSPB8_S57 →	+1.491	+1.320	<.001	<.001	3	7
BRCA	SUPT16H →	-0.416	-1.836	<.001	<.001	3	7
LUAD	API5_S464 →	-0.586	-0.606	<.001	<.001	3	7
UCEC	CAVIN1_S175 →	+1.353	+1.321	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,478 associations by consensus.

HSPB8 vs HSPB8_T87 — BRCA

Explore this scatter interactively →