HSPB6

Across TCGA patient cohorts, HSPB6 protein abundance is significantly associated with the protein abundance of many other proteins, with 28,931 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HSPB6-associated proteins across cancer lineages are SOD3, SYNPO2_S363, and HSPB7. Each is linked with HSPB6 in more than 9 cancer types. Because this analysis shows association rather than direction, both HSPB6-to-partner and partner-to-HSPB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB6 versus SOD3 in PDAC, with a Pearson correlation of 0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB6→partner) and Y-score (partner→HSPB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SOD3 →	+0.857	+1.088	<.001	<.001	3	10
BRCA	SYNPO2_S363 →	+1.639	+1.455	<.001	<.001	3	10
HNSC	HSPB7 →	+1.817	+1.348	<.001	<.001	3	10
HNSC	PYGM →	+1.631	+1.350	<.001	<.001	3	10
COAD	CORO2B →	+1.123	+1.040	<.001	<.001	3	9
CCRCC	DCN →	+1.008	+1.067	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,931 associations by consensus.

HSPB6 vs SOD3 — PDAC

Explore this scatter interactively →