HSPB2-C11orf52

Across TCGA patient cohorts, HSPB2-C11orf52 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,692 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSPB2-C11orf52-associated GO terms across cancer lineages are Pulmonary valve morphogenesis, Obsolete positive regulation of ER-associated ubiquitin-dependent protein catabolic process, and Regulation of cellular response to transforming growth factor beta stimulus. Each is linked with HSPB2-C11orf52 in more than 16 cancer types. Because this analysis shows association rather than direction, both HSPB2-C11orf52-to-partner and partner-to-HSPB2-C11orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pulmonary valve morphogenesis grouped by HSPB2-C11orf52-low versus HSPB2-C11orf52-high in COAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB2-C11orf52→partner) and Y-score (partner→HSPB2-C11orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Pulmonary valve morphogenesis →	+0.060	+0.010	<.001	<.001	3	17
COAD	Obsolete positive regulation of ER-associated ubiquitin-dependent protein catabolic process →	+0.064	+0.009	<.001	<.001	3	17
THYM	Regulation of cellular response to transforming growth factor beta stimulus →	+0.044	+0.016	<.001	<.001	3	16
COAD	Positive regulation of basement membrane assembly involved in embryonic body morphogenesis →	+0.063	+0.009	<.001	<.001	3	16
STAD	Positive regulation of cell-substrate adhesion →	+0.043	+0.018	<.001	<.001	3	16
THYM	Muscle cell migration →	+0.046	+0.010	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,692 associations by consensus.

Pulmonary valve morphogenesis by HSPB2-C11orf52 expression — COAD

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