HSPB11

Across TCGA patient cohorts, HSPB11 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,969 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HSPB11-associated proteins across cancer lineages are HAT1, NRDC, and FAF1. Each is linked with HSPB11 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSPB11-to-partner and partner-to-HSPB11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB11 versus HAT1 in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB11→partner) and Y-score (partner→HSPB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HAT1 →	+0.442	+0.453	<.001	<.001	3	6
OV	NRDC →	+0.236	+0.555	<.001	<.001	3	6
OV	FAF1 →	+0.490	+0.627	<.001	.001	3	5
PDAC	MCM3_S160 →	+1.136	+0.335	<.001	<.001	3	4
COAD	KIF2C →	+0.957	+0.533	<.001	.001	3	4
PDAC	TTC4 →	+0.317	+0.441	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,969 associations by consensus.

HSPB11 vs HAT1 — GBM

Explore this scatter interactively →