HSPA8P6

Across TCGA patient cohorts, HSPA8P6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,540 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HSPA8P6-associated GO terms across cancer lineages are Regulation of protein ubiquitination, rRNA metabolic process, and Protein folding. Each is linked with HSPA8P6 in more than 11 cancer types. Because this analysis shows association rather than direction, both HSPA8P6-to-partner and partner-to-HSPA8P6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein ubiquitination grouped by HSPA8P6-low versus HSPA8P6-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA8P6→partner) and Y-score (partner→HSPA8P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of protein ubiquitination →	+0.044	+0.028	.002	.005	3	12
ESCA	rRNA metabolic process →	+0.074	+0.041	<.001	<.001	3	11
ESCA	Protein folding →	+0.070	+0.039	<.001	.003	3	11
ESCA	tRNA processing →	+0.041	+0.035	.001	.001	3	11
ESCA	mRNA 3'-end processing →	+0.066	+0.041	<.001	.001	3	10
ESCA	Glycosylation →	+0.035	+0.034	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,540 associations by consensus.

Regulation of protein ubiquitination by HSPA8P6 expression — ESCA

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