HSPA8P6

Across TCGA pan-cancer cohorts, HSPA8P6 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of HSPA8P6’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HSPA8P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HSPA8P6 is over-expressed in tumor, although a few such as THCA and STAD show the opposite, repressed pattern.

COAD, BRCA, and THCA are the cancer types where HSPA8P6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPA8P6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.022	.023	4	view →
BRCA	All	III,IV	+0.010	.024	2	view →
THCA	All	II,III,IV	−0.009	.037	2	view →
STAD	Female	III,IV	−0.065	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

HSPA8P6–COAD

Open the COAD breakdown →