HSPA8P6

Across TCGA pan-cancer cohorts, HSPA8P6 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated HSPA8P6 data layer.

The strongest signal is observed in thymoma (THYM), where higher HSPA8P6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HSPA8P6 expression acts as an unfavorable survival marker, although some lineages such as SKCM and GBM show a favorable association.

THYM, HNSC, and BRCA are the cancer types where HSPA8P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	III,IV	0.212	0.953	.009	42	view →
HNSC	OS	Tertile	III,IV	0.246	0.571	.006	36	view →
BRCA	OS	Tertile	III,IV	0.662	0.850	.003	36	view →
KIRC	DFS	Tertile	IV	0.309	0.527	.022	33	view →
CHOL	DFS	Tertile	All	0.113	0.514	.027	27	view →
SKCM	OS	Tertile	III,IV	0.894	0.677	.015	24	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
LUSC	OS	Tertile	III,IV	0.386	0.800	.002	18	view →
UCEC	DFS	Tertile	II,III,IV	0.540	0.751	.029	18	view →
STAD	OS	Median	IV	0.238	0.731	.001	14	view →
GBM	OS	Tertile	All	0.350	0.225	.003	9	view →
PCPG	DFS	Tertile	All	0.448	0.857	.023	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

HSPA8P6–THYM (OS)

Open the THYM breakdown →