heat shock protein family A (Hsp70) member 8 pseudogene 5Genealiases: []
Q-omics provides the consensus-scored HSPA8P5 profile across patient tissues and cancer cell-line models. HSPA8P5 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, HSPA8P5 is differentially expressed in 9, with the highest sampling consensus in COAD. Additionally, HSPA8P5 RNA expression shows 16,392 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight UVM, COAD, and ACC as cancer lineages where HSPA8P5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HSPA8P5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HSPA8P5 survival associations across molecular data types. HSPA8P5 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HSPA8P5 RNA expression–survival associations across cancer types. High HSPA8P5 expression shows unfavorable associations in UVM, ACC, LIHC and STAD, but favorable associations in COAD and READ. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify UVM as the clearest survival context for HSPA8P5 RNA expression.
This table summarizes HSPA8P5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for HSPA8P5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HSPA8P5 shows higher tumor expression in COAD, BRCA, BLCA, LIHC, UCEC and LUAD. The COAD box plot shows higher HSPA8P5 RNA expression in tumor versus normal tissue (log2 FC = +0.764, t-test p < 0.001).
This table shows molecular features associated with HSPA8P5 in patient tissues and cancer cell lines. In patient samples, HSPA8P5 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
