Across TCGA patient cohorts, HSPA14 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,139 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPA14-associated proteins across cancer lineages are UPF2, CUL2, and LARP4B. Each is linked with HSPA14 in more than 7 cancer types. Because this analysis shows association rather than direction, both HSPA14-to-partner and partner-to-HSPA14 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA14→partner) and Y-score (partner→HSPA14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UPF2 →	+0.273	+0.438	<.001	<.001	3	8
BRCA	CUL2 →	+0.252	+0.506	<.001	<.001	3	7
OV	LARP4B →	+0.398	+0.622	.001	.002	2	8
GBM	RNF20 →	+0.288	+0.393	<.001	<.001	3	7
GBM	RNF40 →	+0.291	+0.498	<.001	<.001	3	7
OV	NUDT5 →	+0.416	+0.341	.007	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,139 associations by consensus.

Exploration

HSPA14 survival (RNA) · tumor vs normal (RNA) · all HSPA14 data types