Across TCGA patient cohorts, HSP90B3P mutation is significantly associated with the RNA expression of many other genes, with 557 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSP90B3P-associated genes across cancer lineages are RNU4-28P, RNU6-159P, and RNU1-17P. Each is linked with HSP90B3P in more than 2 cancer types. Because this analysis shows association rather than direction, both HSP90B3P-to-partner and partner-to-HSP90B3P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90B3P→partner) and Y-score (partner→HSP90B3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU4-28P →	+0.144	+3.771	<.001	.002	3	3
HNSC	RNU6-159P →	+0.274	+7.954	<.001	.008	3	2
UCEC	RNU1-17P →	+0.203	+2.613	.002	.007	3	2
LUSC	RNA5SP476 →	+0.117	+3.993	<.001	.009	3	2
SKCM	RPS3AP29 →	+0.128	+4.190	<.001	.001	3	1
SKCM	RNU6-634P →	+0.134	+4.186	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 557 associations by consensus.

Exploration

HSP90B3P survival (RNA) · tumor vs normal (RNA) · all HSP90B3P data types