HSD3BP3

Across TCGA patient cohorts, HSD3BP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,737 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSD3BP3-associated proteins across cancer lineages are PURB, GNG7, and TNS2_S120. Each is linked with HSD3BP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both HSD3BP3-to-partner and partner-to-HSD3BP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD3BP3 versus PURB in HNSC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3BP3→partner) and Y-score (partner→HSD3BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PURB →	+0.272	+0.294	<.001	.002	3	4
OV	GNG7 →	+0.303	+0.128	.005	<.001	3	4
UCEC	TNS2_S120 →	+0.559	+0.511	.001	.009	3	3
OV	TTC7B →	+0.290	+0.142	.003	<.001	3	3
HNSC	UBE2L6 →	-0.424	-0.340	<.001	<.001	3	3
PDAC	USP20_S333 →	-0.411	-0.679	.006	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,737 associations by consensus.

HSD3BP3 vs PURB — HNSC

Explore this scatter interactively →