HSD17B7

Across TCGA patient cohorts, HSD17B7 protein abundance is significantly associated with the RNA expression of many other genes, with 7,773 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HSD17B7-associated genes across cancer lineages are KLHL12, CD46, and MPC2. Each is linked with HSD17B7 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSD17B7-to-partner and partner-to-HSD17B7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B7 versus KLHL12 in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B7→partner) and Y-score (partner→HSD17B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KLHL12 →	+0.738	+0.306	.002	<.001	3	6
HNSC	CD46 →	+0.769	+0.358	.006	<.001	3	5
HNSC	MPC2 →	+0.728	+0.363	.005	<.001	3	5
LSCC	SCAMP3 →	+0.472	+0.331	<.001	<.001	3	5
LSCC	MEFV →	-0.702	-0.327	.001	.001	3	4
HNSC	RPS6KC1 →	+0.640	+0.353	.006	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,773 associations by consensus.

HSD17B7 vs KLHL12 — HNSC

Explore this scatter interactively →