Across TCGA patient cohorts, HSD17B11 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,798 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSD17B11-associated proteins across cancer lineages are PARVA, PRKDC, and TIMM44. Each is linked with HSD17B11 in more than 4 cancer types. Because this analysis shows association rather than direction, both HSD17B11-to-partner and partner-to-HSD17B11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B11→partner) and Y-score (partner→HSD17B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PARVA →	+0.428	+0.535	<.001	<.001	3	5
LSCC	PRKDC →	-0.320	-0.565	<.001	<.001	3	5
OV	TIMM44 →	-0.405	-0.560	.003	.008	3	4
BRCA	TNS2 →	+0.298	+0.722	<.001	<.001	3	4
LSCC	TNS2_S102 →	+0.661	+0.519	<.001	<.001	3	4
BRCA	MIOS_S766 →	-0.464	-0.633	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,798 associations by consensus.

Exploration

HSD17B11 survival (RNA) · tumor vs normal (RNA) · all HSD17B11 data types