Across TCGA patient cohorts, HSD17B11 protein abundance is significantly associated with the RNA expression of many other genes, with 18,514 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSD17B11-associated genes across cancer lineages are NCF4, TLR8, and JAK3. Each is linked with HSD17B11 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSD17B11-to-partner and partner-to-HSD17B11 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B11→partner) and Y-score (partner→HSD17B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NCF4 →	+0.894	+0.508	<.001	.001	3	5
OV	TLR8 →	+1.101	+0.567	<.001	<.001	3	5
OV	JAK3 →	+1.146	+0.413	<.001	<.001	3	5
OV	TMEM176B →	+1.128	+0.460	.001	<.001	3	5
OV	BIN2 →	+0.975	+0.450	<.001	<.001	3	5
OV	ITK →	+0.957	+0.478	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,514 associations by consensus.

Exploration

HSD17B11 survival (RNA) · tumor vs normal (RNA) · all HSD17B11 data types