HSD17B11

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HSD17B11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,954 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HSD17B11-associated GO terms across cancer lineages are Androgen catabolic process, Steroid catabolic process, and Spliceosomal tri-snRNP complex assembly. Each is linked with HSD17B11 in more than 9 cancer types. Because this analysis shows association rather than direction, both HSD17B11-to-partner and partner-to-HSD17B11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B11→partner) and Y-score (partner→HSD17B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTAndrogen catabolic process →+0.681+1.660<.001<.001310
SOFT_TISSUESteroid catabolic process →+0.298+1.383<.001<.001310
OESOPHAGUSSpliceosomal tri-snRNP complex assembly →-0.135-2.010.005.00139
SOFT_TISSUEAndrogen metabolic process →+0.135+1.587<.001<.00139
BLOOD_LeukemiaHistamine metabolic process →+0.850+0.924<.001<.00139
SOFT_TISSUESteroid hormone biosynthetic process →+0.085+1.111<.001.00638
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,954 associations by consensus.

Exploration