HSD11B1L

Across TCGA patient cohorts, HSD11B1L RNA expression is significantly associated with the protein abundance of many other proteins, with 13,815 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSD11B1L-associated proteins across cancer lineages are ISG20, PSME2, and ARMC1. Each is linked with HSD11B1L in more than 5 cancer types. Because this analysis shows association rather than direction, both HSD11B1L-to-partner and partner-to-HSD11B1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD11B1L versus ISG20 in HNSC, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD11B1L→partner) and Y-score (partner→HSD11B1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ISG20 →	-0.714	-0.557	<.001	<.001	3	6
LSCC	PSME2 →	-0.440	-0.691	<.001	<.001	3	6
GBM	ARMC1 →	+0.228	+0.525	.001	<.001	3	4
OV	KIF21A_S1212 →	-0.758	-1.053	<.001	<.001	3	4
BRCA	ATP2A3 →	-0.691	-0.624	.001	.001	3	4
BRCA	COX20 →	+0.478	+0.791	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,815 associations by consensus.

HSD11B1L vs ISG20 — HNSC

Explore this scatter interactively →