HSD11B1L

Across TCGA cell cohorts, HSD11B1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,649 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HSD11B1L-associated GO terms across cancer lineages are ATP biosynthetic process, Purine nucleoside triphosphate metabolic process, and Purine nucleoside triphosphate biosynthetic process. Each is linked with HSD11B1L in more than 11 cancer types. Because this analysis shows association rather than direction, both HSD11B1L-to-partner and partner-to-HSD11B1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP biosynthetic process grouped by HSD11B1L-low versus HSD11B1L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD11B1L→partner) and Y-score (partner→HSD11B1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	ATP biosynthetic process →	+0.095	+1.079	<.001	<.001	3	12
BONE	Purine nucleoside triphosphate metabolic process →	+0.075	+0.866	<.001	.001	3	11
BONE	Purine nucleoside triphosphate biosynthetic process →	+0.108	+1.353	<.001	<.001	3	11
BONE	Purine ribonucleoside triphosphate biosynthetic process →	+0.108	+1.353	<.001	<.001	3	11
BONE	Oxidative phosphorylation →	+0.079	+0.974	<.001	<.001	3	11
STOMACH	Negative regulation of myoblast fusion →	+0.098	+0.880	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

ATP biosynthetic process by HSD11B1L expression — BONE

Explore this box plot interactively →