HSD11B1L

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HSD11B1L mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HSD11B1L-associated genes across cancer lineages are OR2D3. Each is linked with HSD11B1L in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD11B1L-to-partner and partner-to-HSD11B1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2D3 grouped by HSD11B1L-low versus HSD11B1L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD11B1L→partner) and Y-score (partner→HSD11B1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR2D3 →+0.027+4.095.001.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR2D3 by HSD11B1L expression — LARGE_INTESTINE

Box plot of OR2D3 in HSD11B1L-low vs HSD11B1L-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration