HS6ST2-AS1

Across TCGA patient cohorts, HS6ST2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,966 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HS6ST2-AS1-associated GO terms across cancer lineages are Rac protein signal transduction, Telencephalon development, and Non-motile cilium assembly. Each is linked with HS6ST2-AS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HS6ST2-AS1-to-partner and partner-to-HS6ST2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rac protein signal transduction grouped by HS6ST2-AS1-low versus HS6ST2-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HS6ST2-AS1→partner) and Y-score (partner→HS6ST2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Rac protein signal transduction →	+0.079	+0.052	<.001	<.001	3	9
STAD	Telencephalon development →	+0.061	+0.049	<.001	<.001	3	9
STAD	Non-motile cilium assembly →	+0.060	+0.051	<.001	<.001	3	9
STAD	Positive regulation of neuron projection development →	+0.065	+0.059	<.001	<.001	3	8
STAD	Pallium development →	+0.063	+0.051	<.001	<.001	3	8
TGCT	Cerebral cortex cell migration →	+0.071	+0.028	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,966 associations by consensus.

Rac protein signal transduction by HS6ST2-AS1 expression — STAD

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