HS6ST2-AS1

Across TCGA pan-cancer cohorts, HS6ST2-AS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of HS6ST2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HS6ST2-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HS6ST2-AS1 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

COAD and KIRP are the cancer types where HS6ST2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HS6ST2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	IV	+0.100	.040	3	view →
KIRP	Male	All	−0.030	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

HS6ST2-AS1–COAD

Open the COAD breakdown →