HS1BP3

Across TCGA patient cohorts, HS1BP3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,982 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HS1BP3-associated genes across cancer lineages are LAPTM4A, SLC66A3, and DUSP3. Each is linked with HS1BP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HS1BP3-to-partner and partner-to-HS1BP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS1BP3 versus LAPTM4A in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HS1BP3→partner) and Y-score (partner→HS1BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LAPTM4A →	+0.384	+0.319	<.001	<.001	3	6
LSCC	SLC66A3 →	+0.633	+0.295	<.001	<.001	3	6
LUAD	DUSP3 →	+0.519	+0.293	<.001	<.001	3	5
OV	PHYH →	+0.892	+0.300	<.001	<.001	3	4
LUAD	BRI3 →	+0.635	+0.262	<.001	<.001	3	4
OV	GBA →	+0.575	+0.221	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,982 associations by consensus.

HS1BP3 vs LAPTM4A — GBM

Explore this scatter interactively →