HPSE2

Across TCGA patient cohorts, HPSE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,330 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HPSE2-associated proteins across cancer lineages are KANK2, TNS1, and ARHGAP6. Each is linked with HPSE2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HPSE2-to-partner and partner-to-HPSE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HPSE2 versus KANK2 in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HPSE2→partner) and Y-score (partner→HPSE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KANK2 →	+0.588	+0.683	<.001	<.001	3	7
UCEC	TNS1 →	+0.670	+0.782	<.001	<.001	3	7
UCEC	ARHGAP6 →	+0.647	+0.802	<.001	.002	3	7
HNSC	SYNPO2 →	+1.029	+0.532	<.001	.001	3	6
UCEC	SYNPO2_S363 →	+1.209	+0.723	<.001	<.001	3	6
BRCA	C11orf96 →	+0.451	+0.595	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,330 associations by consensus.

HPSE2 vs KANK2 — UCEC

Explore this scatter interactively →