HOXC10

Across TCGA patient cohorts, HOXC10 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,652 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HOXC10-associated proteins across cancer lineages are HOXC10_S189, SIGLEC7_S441, and TBC1D2B. Each is linked with HOXC10 in more than 4 cancer types. Because this analysis shows association rather than direction, both HOXC10-to-partner and partner-to-HOXC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXC10 versus HOXC10_S189 in LSCC, with a Pearson correlation of 0.91.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC10→partner) and Y-score (partner→HOXC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HOXC10_S189 →	+1.827	+2.064	<.001	<.001	3	5
UCEC	SIGLEC7_S441 →	-1.286	-2.530	.006	.006	3	4
GBM	TBC1D2B →	-0.245	-1.051	.002	<.001	3	3
HNSC	N4BP1 →	-0.209	-0.888	.002	.002	3	3
LSCC	PIP4K2A →	-0.273	-0.999	.001	.003	3	3
HNSC	RHPN2 →	+0.546	+1.234	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,652 associations by consensus.

HOXC10 vs HOXC10_S189 — LSCC

Explore this scatter interactively →