HOXC10

Across TCGA patient cohorts, HOXC10 protein abundance is significantly associated with the RNA expression of many other genes, with 933 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HOXC10-associated genes across cancer lineages are HOXC6, SLC5A1, and DHRS7. Each is linked with HOXC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXC10-to-partner and partner-to-HOXC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXC10 versus HOXC6 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC10→partner) and Y-score (partner→HOXC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HOXC6 →	+0.633	+0.673	<.001	<.001	3	2
LUAD	SLC5A1 →	+1.669	+1.824	.002	<.001	3	1
LUAD	DHRS7 →	+1.046	+2.117	.006	.004	3	1
LUAD	PLS3 →	+2.116	+2.153	.001	.001	3	1
LUAD	GABRE →	+1.686	+1.545	.009	.005	3	1
LUAD	CDADC1 →	+0.459	+2.103	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 933 associations by consensus.

HOXC10 vs HOXC6 — BRCA

Explore this scatter interactively →