HOXC10

Across TCGA cell cohorts, HOXC10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,454 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HOXC10-associated GO terms across cancer lineages are Embryonic skeletal joint morphogenesis, Peptidyl-lysine oxidation, and Response to bleomycin. Each is linked with HOXC10 in more than 6 cancer types. Because this analysis shows association rather than direction, both HOXC10-to-partner and partner-to-HOXC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic skeletal joint morphogenesis grouped by HOXC10-low versus HOXC10-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC10→partner) and Y-score (partner→HOXC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Embryonic skeletal joint morphogenesis →	-0.347	-2.815	.008	.005	3	7
URINARY_TRACT	Peptidyl-lysine oxidation →	+1.006	+2.528	.002	<.001	3	6
LUNG_SCLC	Response to bleomycin →	+0.120	+2.757	.004	<.001	3	6
LARGE_INTESTINE	Negative regulation of fatty acid transport →	+0.125	+1.137	<.001	.003	3	6
LARGE_INTESTINE	Beige fat cell differentiation →	-0.192	-1.531	<.001	<.001	3	6
OESOPHAGUS	Lipid oxidation →	+0.084	+2.088	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,454 associations by consensus.

Embryonic skeletal joint morphogenesis by HOXC10 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →