HOXB7

Across TCGA patient cohorts, HOXB7 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,358 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HOXB7-associated proteins across cancer lineages are NUF2_S247, SAAL1, and LIN54_S635. Each is linked with HOXB7 in more than 3 cancer types. Because this analysis shows association rather than direction, both HOXB7-to-partner and partner-to-HOXB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXB7 versus NUF2_S247 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB7→partner) and Y-score (partner→HOXB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NUF2_S247 →	+0.667	+0.797	<.001	<.001	3	4
LSCC	SAAL1 →	+0.454	+1.004	<.001	<.001	3	4
LUAD	LIN54_S635 →	+0.401	+0.845	.005	.007	3	4
LUAD	WDHD1 →	+0.513	+0.770	.002	.007	3	3
LSCC	TMTC3 →	+0.359	+0.820	<.001	<.001	3	3
LSCC	TOP2A →	+0.753	+0.763	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,358 associations by consensus.

HOXB7 vs NUF2_S247 — LSCC

Explore this scatter interactively →