HOXB-AS3

Across TCGA patient cohorts, HOXB-AS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,131 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible HOXB-AS3-associated GO terms across cancer lineages are Embryonic organ morphogenesis, Embryonic skeletal system morphogenesis, and Embryonic skeletal system development. Each is linked with HOXB-AS3 in more than 22 cancer types. Because this analysis shows association rather than direction, both HOXB-AS3-to-partner and partner-to-HOXB-AS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic organ morphogenesis grouped by HOXB-AS3-low versus HOXB-AS3-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB-AS3→partner) and Y-score (partner→HOXB-AS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Embryonic organ morphogenesis →	+0.046	+0.708	<.001	<.001	3	22
TGCT	Embryonic skeletal system morphogenesis →	+0.050	+0.602	<.001	<.001	3	22
LAML	Embryonic skeletal system development →	+0.057	+2.879	<.001	<.001	2	23
LAML	Definitive hemopoiesis →	+0.092	+2.354	<.001	<.001	2	22
LAML	Glossopharyngeal nerve development →	+1.105	+3.273	<.001	<.001	3	21
LAML	Anterior/posterior pattern specification →	+0.053	+2.731	<.001	<.001	2	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,131 associations by consensus.

Embryonic organ morphogenesis by HOXB-AS3 expression — TGCT

Explore this box plot interactively →